Our history

DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals

Milestones

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1869

The company is founded as the “Nederlandsche Gist- en Spiritusfabriek” (NG&SF).

1879

NG&SF is the first Dutch company to found a works council and employee magazine.

1884

NG&SF builds the Agnetapark, the first workers’ housing in the Netherlands, which today is a national heritage site.

1940s

Production of Penicillin G starts; initially under the code name BACINOL >> read more.

Chemical-based SSPs and SSCs soon follow.

1970s

Under the name “Gist Brocades”, the company rises to become the world’s No. 1 Penicillin G producer.

1983

Construction of newly developed dedicated anaerobic digestion waste water treatment facilities starts at the Delft site.

1990s

Global production and sales network achieved through acquisitions and joint ventures, starting in India, China and then Mexico.

1997

In a joint venture, DSM and Gist Brocades develop the first industrial-scale enzymatic process for beta-lactam antibiotics manufacturing. Commercial production of cefalexin, marketed as "Purilex®", a semi- synthetic cephalosporin, starts.

1998

DSM acquires Gist Brocades. The newly formed leader in beta-lactam antibiotics is called DSM Anti-Infectives (DAI).

2003

The first enzymatically produced amoxicllin called "Purimox®" is commercially introduced to the world. It is the first member of the PureActives® family of Sustainable Antibiotic APIs.

2005 - 2011

Global roll-out of the enzymatic technology for beta-lactam APIs to all sites and worldwide introduction of the PureActives® family of antibiotics.

2011

In a joint venture, Sinochem of China acquires 50% of DAI from DSM to form DSM Sinochem Pharmaceuticals (DSP).

2012

We introduce our first Drug Product (Finished Dosage Formulation), made exclusively using own high-quality enzymatic PureActives® API.

2012

We introduce the first enzymatically produced statin "Atorvastatin from DSP" to the world, further leveraging our enzymatic expertise.

2014

We open a world-class statins plant in Toansa, India. Production of statins starts in the second half of 2014, using our proprietary enzymatic biotechnology route and second generation bio-fuels.

2014

The Sustainable Antibiotics program is launched to address the threat of Antibiotic Resistance and to ensure we do everything we can to guarantee the sustainable, reliable and clean production of our high-quality products.

2014

We offer a comprehensive portfolio of AmoxiClav, statin and anti-fungal Drug Products (Finished Dosage Formulation), made exclusively using our own high-quality enzymatic PureActives® API.

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DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals
DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals
DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals
DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals
DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals
DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals
DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals
DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals
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DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals
DSM Sinochem Pharmaceuticals history from NG&SF via Gist-brocades and DSM to DSM Sinochem Pharmaceuticals